Searchable abstracts of presentations at key conferences in endocrinology

ea0056p294 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2018

Lobeglitazone, a novel thiazolidinedione, improves hepatic steatosis in diet-induced obese mice

choung Sorim , You Bo Ram , Kim Ji Min , Joung Kyong Hye , Kim Hyun Jin , Ku Bon Jeong

Although non-alcoholic fatty liver disease (NAFLD) patients are rapidly growing, there is not optimal therapy to improve NAFLD. NAFLD is strongly associated with insulin resistance. The peroxisome proliferator-activated receptor (PPAR) activator thiazolidinediones (TZD) is an insulin sensitizer, and have been focused as the drug for NAFLD. However, the TZD remain debate as drug of choice on NAFLD because of its conflicting results on the hepatic steatosis and fibrosis. Lobegli...